Publikationen

2017

  • L. Gremer, D. Schölzel, C. Schenk, E. Reinartz, J. Labahn, R. Ravelli, M. Tusche, C. Lopez-Iglesias, W. Hoyer, H. Heise, D. Willbold, G. Schröder, Fibril structure of amyloid-ß(1-42) by cryo-electron microscopy, Science, 2017, 358, 116-119.
  • C. Beumer, A. König, D. Schölzel, B. Uluca, F. Weirich, H. Heise, Methods for complex systems - Isotopically enriched systems, in "Modern Methods in Solid-State NMR: A Practitioners’ Guide" (P. Hodginson, Ed.), Royal Soc. Chem. 2017, in press. ISSN: 2044-253X.

2016

  • T. Viennet, A. Viegas, A. Kuepper, S. Arens, V. Gelev, O. Petrov, T. N. Grossmann, H. Heise, M. Etzkorn, Selective Protein Hyperpolarization in Cell Lysates Using Targeted Dynamic Nuclear Polarization. Angew. Chem. Int. Ed. Engl. 2016, 55, 10746-10750.
  • F. Weirich, L. Gremer, E.A: Mirecka, S. Schiefer, W. Hoyer, H. Heise. Structural Characterization of Fibrils from Recombinant Human Islet Amyloid Polypeptide by Solid-State NMR: The Central FGAILS Segment is Part of the beta-sheet Core, PLoS ONE, 2016, 11, e0161243.

2015

  • W. Hoyer, H. Shaykhalishahi, S. Ayalur-Karunakaran, H. Heise, Structural characterization of alpha-Synuclein amyloids, In The Prion Phenomena in Neurodegenerative Diseases: New Frontiers in Neuroscience (G. Giachin and G. Legname, Eds.), 2015, pp 111-128, Nova Biomedical.

2014

  • H. Müller, O. Brener, O. Andreoletti, T. Piechatzek, D Willbold, G. Legname, H. Heise, Progress towards structural understanding of infectious sheep PrP-amyloid, Prion, 2014, 8, 344-358.
  • S.-C. Zhang, L. Gremer, H. Heise, P. Janning, A. Shymanets, I.C. Cirstea, E. Krause, B. Nürnberg, M.R. Ahmadian,. Liposome Reconstitution and Modulation of Recombinant Prenylated Human Rac1 by GEFs, GDI1 and Pak1. PLoS ONE, 2014, 9, e102425.

2013

2011

  • R. Schneider, M. C.  Schumacher, H. Mueller, D. Nand, V. Klaukien, H. Heise, D. Riedel, G. Wolf, E. Behrmann, S. Raunser, R. Seidel, M. Engelhard, M. Baldus, Structural Characterization of Polyglutamine Fibrils by Solid-State NMR Spectroscopy. J. Mol. Biol. 2011, 412, 121-136.

2010

  • A. Kumar, H. Heise, M.J.J. Blommers, P. Krastel, E. Schmitt, F. Petersen, E.M. Mandelkow, T. Carlomagno, C. Griesinger, M. Baldus,Interaction of Epothilone B (Patupilone) with Microtubules, As Detected by Two-Dimensional Solid-State NMR Spectroscopy, Angew. Chem. Int. Ed. 2010, 49, 7504-7507.

2009

  • D.P. Karpinar, M.B.G. Balija, S. Kügler, F. Opazo, N. Rezaei-Ghaleh, N. Bender, H.-Y. Kim, G. Taschenberger, B.H. Falkenburger, H. Heise, A. Kumar, D. Riedel, L. Fichtner, A. Voigt, G.H. Braus, K. Giller, S. Becker, A. Herzig, M. Baldus, H. Jäckle, S. Eimer, J.B. Schulz, C. Griesinger, M. Zweckstetter, Pre-fibrillar alpha-Synuclein Variants with Impaired beta-Structure Increase Neurotoxicity in Parkinson`s Disease Models, EMBO J.,2009, 28, 3256 - 3268.

2008

  • H. Heise, Solid-State NMR Spectroscopy of Amyloid Proteins, ChemBioChem, 2008, 9, 179-189.
  • C. Gardiennet, A. Loquet, M. Etzkorn, H. Heise, M. Baldus, A. Böckmann, Structural constraints for the Crh protein from solid-state NMR experiments, J. Biomol. NMR, 2008, 40, 239-250.
  • H. Heise, M.S. Celej, S. Becker, D. Riedel, A. Pelah, A. Kumar, T.M. Jovin, M. Baldus, Solid-state NMR reveals structural differences between fibrils of wild-type and disease-related A53T mutant alpha-synuclein, J. Mol. Biol. 2008, 380, 444-450.

2007

  • H.-Y. Kim, H. Heise, C.O. Fernandez, M. Baldus, M. Zweckstetter, Correlation of Amyloid Fibril beta-Structure with the Unfolded State of alpha-Synuclein, ChemBioChem, 2007, 8, 1671-1674.

2006

2005

  • O. Benedi Borobia, P. Guionneau, H. Heise, F.H. Köhler, L. Ducasse, J. Vidal-Gancedo, J. Veciana, S. Golhen, L. Ouahab, J.-P. Sutter: Discrepancy Between the Spin Distribution and the Magnetic Ground State for a Tri-Aminoxyl Substituted Triphenylphosphine Oxide Derivative, Chem. Eur. J. 2005, 11, 128-139.
  • H. Heise, K. Seidel, M. Etzkorn, S. Becker, M. Baldus: 3D MAS Solid State NMR Spectroscopy for Resonance Assignment and Structure Elucidation of Proteins. Novel Pulse Schemes and Sensitivity Considerations, J. Magn. Reson. 2005, 173, 64-74.
  • H. Heise, S. Luca, B.L. deGroot, H. Grubmüller, M. Baldus: Probing Conformational Distributions by High-Resolution Solid-State NMR and MD Simulations: Application to Neurotensin, Biophys. J. 2005, 89, 2113-2120.
  • S. Luca, H. Heise, A. Lange, M. Baldus: Investigation of Ligand-receptor Interactions by High-Resolution Solid-State NMR, Arch. Pharm. Chem. Life Sci., 2005, 338, 217-228.
  • K. Seidel, M. Etzkorn, H. Heise, S. Becker, M. Baldus: High-resolution solid-state NMR studies on uniformly [13C,15N] labeled Ubiquitin, ChemBioChem, 2005, 6, 1638-1647.
  • O.C. Andronesi, S. Becker, K. Seidel, H. Heise, H. S. Young, M. Baldus, Determination of Membrane Protein Structure and Dynamics by Magic-Angle-Spinning Solid-State NMR, J. Am. Chem. Soc. 2005, 127, 12965 - 12974.
  • H. Heise, W. Hoyer, S. Becker, O.C. Andronesi, D. Riedel, M. Baldus, Molecular Level Secondary Structure, Polymorphism and Dynamics of Full-length alpha-Synuclein Fibrils Studied by Solid-State NMR, PNAS, 2005, 102,15871-15876.

2004

  • D. C. Sporer, H. Heise, K.Wurst, D. Ruiz-Molina, H. Kopacka, P. Jaitner, F. H. Köhler, J.J. Novoa, J. Veciana: Magneto-Structural Characterization of Metallocene-Bridged Nitronyl Nitroxide Diradicals by X-Ray, Magnetic Measurements, Solid-state NMR Spectroscopy, and Ab Initio Calculations, Chem. Eur. J. 2004, 10, 1355-1365.
  • C. Rancurel, H. Heise, F.H. Köhler, U. Schatzschneider, E. Rentschler, J. Vidal-Gancedo, J. Veciana, J.-P. Sutter: Spin Transfer and Magnetic Interaction via Phosphorus in Nitronyl Nitroxide Radical-Substituted Triphenylphosphine Derivatives, J. Phys. Chem. A, 2004, 108, 5903 -5914.
  • V.K. Koltover, J.W. Logan, H. Heise,V.P. Bubnov, Y.I. Estrin, V.P. Lodygina, A. Pines: Diamagneitc Clusters of Paramagnetic Endometallofullerenes: A Solid-State MAS NMR Study, J. Phys. Chem. B, 2004, 108, 12450 -12455.
  • R. Ziessel, C. Stroh, H. Heise, F.H. Köhler, P. Turek, N. Claiser, M. Souhassou, C. Lecomte: Strong Exchange Interactions between Two Radicals Attached to Nonaromatic Spacers Deduced from Magnetic, EPR, NMR, and Electron Density Measurements, J. Am. Chem. Soc. 2004, 126, 12604-12613.
  • K. Seidel, A. Lange, S. Becker, C.E. Hughes, H. Heise, M. Baldus: Protein Solid-State NMR Resonance Assignments from (13C,13C) Correlation Spectroscopy, Phys. Chem. Chem. Phys. 2004, 6, 5090-5093.

2003

  • A. Böckmann, A. Lange, A. Galinier, S. Luca, N. Giraud, M. Juy, H. Heise, R. Montserret, F. Penin, M. Baldus: Solid State NMR Sequential Resonance Assignments and Conformational Analysis, of the 2x10.4 kDa Dimeric Form of the Bacillus Subtilis Protein Crh, J. Biomol. NMR, 2003, 27, 323-339.
  • S. Luca, H. Heise, M. Baldus: High-Resolution Solid State NMR applied to Polypeptides and Membrane Proteins, Acc. Chem. Res. 2003, 36, 858-865.

2002

  • H. Heise, D. Sakellariou, C. A. Meriles, A. Moule, A. Pines: 2-Dimensional High-resolution NMR Spectra in Matched Bo and B1 Field Gradients, J. Magn. Reson. 2002, 156, 146-151.
  • H. Heise, F. H. Köhler, M. Herker, W. Hiller: Solid-state NMR investigations on paramagnetic metallocenium salts: Probing intra- and intermolecular spin density distribution, J. Am. Chem. Soc. 2002, 124, 10823-10832.
  • S. Wi, H. Heise, A. Pines: Reintroducing Anisotropic Interactions in Magic-Angle-Spinning NMR of Half-Integer Quadrupolar Nuclei: 3D MQMAS, J. Am. Chem. Soc. 2002, 124, 10652-10653.

2001

2000

  • G. W. Rabe, H. Heise, L. M. Liable-Sands, I. A. Guzei, A. L. Rheingold: Synthesis and X-ray Crystal structure Determination of two monomeric Alkali Metal Phosphide Derivatives: [MPH(tBu3Mes)](18-crown-6) (M=K, Rb). J. Chem.Soc., Dalton Trans, 2000, 12, 1863-1866.

1999

  • H. Heise, F. H. Köhler, E. Brouwer, R. K. Harris, S. Steuernagel: 59Co second-order quadrupolar effects in the 13C CP/MAS-NMR spectra of the cobaltocenium salts [Cp*2Co]+[PF6]- and [Cp*CpCo]+[PF6]-. Magn. Reson. Chem. 1999, 37, 573-578.
  • L. Djakovitch, H. Heise, K. Köhler: Heck reactions between aryl halides and olefins catalysed by Pd-complexes entrapped into zeolites NaY. J. Organomet. Chem. 1999, 584, 16-26.
  • H. Heise, F. H. Köhler, J. Veciana, F. Mota, J. J. Novoa: Determination of the Spin Distribution in Nitronylnitroxides by Solid-State-NMR Spectroscopy. J. Am. Chem. Soc. 1999, 121, 9659-9667.

1998

  • G. W. Rabe, S. Kheradmandan, H. Heise, I. A. Guzei, L. M. Liable-Sands, A. L. Rheingold: Influence of Donor Solvents on the Molecular Structure of KP(tBu)Ph. Main Group Chem. 1998, 2, 221 - 228.
  • G. W. Rabe, H. Heise, G. P. A. Yap, L. M. Liable-Sands, I. A. Guzei, A. L. Rheingold: Molecular Structures of the Heavier Alkali Metal Salts of Supermesitylphosphane: A Systematic Investigation. Inorg. Chem. 1998, 37, 4235 - 4245.

 

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